Due to the immature development of the newborn's body and the particularity of pharmacokinetics, the absorption, distribution, metabolism, and excretion of drugs are significantly different from those of older children. Therefore, there are many special requirements for neonatal medication, and many clinical drugs are faced. Limitations and difficulties require special care, and some drugs with more toxic side effects should not be used.
Sodium nitroprusside is a powerful, fast-acting vasodilator, red-brown crystal or powder; odorless or almost odorless. It is a strong dilator that acts directly on the arteriovenous vascular bed. It is used to treat hypertension emergency, such as hypertension crisis, hypertensive encephalopathy, malignant hypertension, adrenal pheochromocytoma, controlled hypotension during surgical anesthesia, acute pulmonary edema, acute myocardial infarction and heart failure. The human lethal dose is 7.0 mg / kg. This medicine mainly damages the nervous system and cardiovascular system.
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